Dc. Yang et al., RADIONUCLIDE SIMULTANEOUS DUAL-ISOTOPE STRESS MYOCARDIAL PERFUSION STUDY USING THE 3 WINDOW TECHNIQUE, Clinical nuclear medicine, 18(10), 1993, pp. 852-857
Several methods are available for performing radionuclide stress myoca
rdial perfusion studies. All of these methods require two separate acq
uisition and processing iterations, which is time-consuming and inconv
enient for the patient. The authors introduce a new method using the '
'three window technique'' that they developed to perform simultaneous
dual-isotope imaging for stress myocardial perfusion studies. In addit
ion to Tl-201 and Tc-99m windows centered at 70 KeV and 140 KeV, respe
ctively, a third window centered at 105 KeV, representing scattered ra
dioactivity from Tc-99m, is established. By subtracting the radioactiv
ity in the third window from the radioactivity in the Tl-201 window, '
'crosstalk'' interference is significantly reduced. The simultaneous d
ual-isotope imaging method acquires and processes resting and stress m
yocardial perfusion images simultaneously. It halves imaging time and
doubles patient throughput, improves scheduling flexibility, and reduc
es patient waiting time and discomfort.