Fine needle aspiration (FNA) was performed on 102 hepatic lesions unde
r ultrasound control. Eighty-eight lesions were solid and 14 were cyst
ic. Ninety aspirates provided adequate material for cytodiagnosis. Asp
irates from the solid lesions were assessed for the presence or absenc
e of 20 cytological features. It was found that on a univariate statis
tical analysis, 11 of the features were significantly associated with
hepatocellular carcinomas. Five of these 11 were considered diagnostic
of the lesion on a step-wise multiple linear regression analysis. Two
other features (not included among the 11) were found to be significa
ntly associated with metastatic neoplasms. Cystic lesions were diagnos
ed as being either abscesses, hydatid cysts or congenital cysts. The p
hysical appearance of the cyst fluid proved to be of diagnostic value
in many cases.