RELATIONSHIP OF IL-2, IL-2R (CD25(-2R AND IL-4 WITH DISEASE-ACTIVITY IN SLE PATIENTS()), SOLUBLE IL)

Authors
CUADRADO MJ MARUBAYASHI M ORTEGA C FERNANDEZARCAS N GARCIACOZAR F PENA J SANCHEZGUIJO P SANTAMARIA M
Citation
Mj. Cuadrado et al., RELATIONSHIP OF IL-2, IL-2R (CD25(-2R AND IL-4 WITH DISEASE-ACTIVITY IN SLE PATIENTS()), SOLUBLE IL), Lupus, 2(4), 1993, pp. 257-260
Citations number
23
Categorie Soggetti
Medicine, General & Internal",Rheumatology
Journal title
Lupus → ACNP
ISSN journal
09612033
Volume
2
Issue
4
Year of publication
1993
Pages
257 - 260
Database
ISI
SICI code
0961-2033(1993)2:4<257:ROII(A>2.0.ZU;2-C
Abstract
The plasma levels of interleukin-4 (IL-4), interleukin-2 (IL-2), solub le receptor of IL-2 (IL-2R) and T cell expression of IL-2 receptor cha in (CD25(+)) were determined in an attempt to relate these parameters with disease activity in systemic lupus erythematosus (SLE). IL-4, IL- 2 and sIL-2R plasma levels of SLE patients were significantly higher t han those of the control group (P<0.05) while CD25(+) expression was s imilar in both groups. Only sIL-2R levels were significantly higher (P <0.05) in active than in inactive patients.