EVOLUTION OF LEFT-VENTRICULAR HYPERTROPHY AND FUNCTION DURING LONG-TERM TREATMENT OF SYSTEMIC HYPERTENSION WITH ENALAPRIL

Citation
Jr. Gonzalezjuanatey et al., EVOLUTION OF LEFT-VENTRICULAR HYPERTROPHY AND FUNCTION DURING LONG-TERM TREATMENT OF SYSTEMIC HYPERTENSION WITH ENALAPRIL, The American journal of cardiology, 79(3), 1997, pp. 373
Citations number
16
Categorie Soggetti
Cardiac & Cardiovascular System
ISSN journal
00029149
Volume
79
Issue
3
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)79:3<373:EOLHAF>2.0.ZU;2-C
Abstract
Continued treatment of hypertensive patients with enalapril reduced le ft ventricular (LV) hypertrophy steadily over a period of 5 years (by which time gross; structural parameters were normal) and produced no f urther reduction during the following 2 years. Temporary suspension of treatment after 5-year follow-up gave rise to an increase in blood pr essure, and to deterioration of LV isovolumic relaxation time and dece leration of the ventricular filling E wave, both of which chiefly refl ect the active relaxation of the ventricle.