NEW HETEROCYCLIC BRIDGEHEAD NITROGEN-COMPOUNDS SYNTHESIS OF 1-(P-TOSYL)PYRAZOLO[1,5-A]PYRIMIDINES AND PYRAZOLO[5,1-C]-[1,2,4]-TRIAZINE DERIVATIVES

Interaction of 3-amino-1,5-dihydro-1-(p-tosyl)pyrazole with ethyl acet oacetate, acrylonitrile and acetyl acetone afforded the corresponding 1-(p-tosyl)pyrazolo[1,5-a]pyrimidine derivatives. Diazotization of the starting compound and subsequent coupling with bifunctionally active nitriles yielded the corresponding pyrazolo[5,1-c]-[1,2,4]-triazine de rivatives. IR and H-1 NMR spectra for all of the hitherto prepared com pounds are in good agreement with the proposed structures.