BACITRACIN PRODUCTION BY A NEW STRAIN OF BACILLUS-SUBTILIS - EXTRACTION, PURIFICATION, AND CHARACTERIZATION

Authors
AZEVEDO EC RIOS EM FUKUSHIMA K CAMPOSTAKAKI GM
Citation
Ec. Azevedo et al., BACITRACIN PRODUCTION BY A NEW STRAIN OF BACILLUS-SUBTILIS - EXTRACTION, PURIFICATION, AND CHARACTERIZATION, Applied biochemistry and biotechnology, 42(1), 1993, pp. 1-9
Citations number
32
Categorie Soggetti
Biothechnology & Applied Migrobiology",Biology
Journal title
Applied biochemistry and biotechnology → ACNP
ISSN journal
02732289
Volume
42
Issue
1
Year of publication
1993
Pages
1 - 9
Database
ISI
SICI code
0273-2289(1993)42:1<1:BPBANS>2.0.ZU;2-2
Abstract
A new strain of Bacillus subtilis C 126 was isolated from sugar cane f ermentation and produced an antibiotic that inhibited the growth of Mi crococcus flavus. The production of the antibiotic in culture medium f ollowed to extraction with n-butanol, thin layer chromatography, and m icrobiological tests indicated that a polypeptide antibiotic was produ ced. The fraction obtained by Sephadex G-25 column and analyzed by HPL C indicated that bacitracin complex was produced.