EXACERBATION OF PSORIASIS DUE TO INTERFERON-ALPHA TREATMENT OF CHRONIC ACTIVE HEPATITIS

Authors
GEORGETSON MJ YARZE JC LALOS AT WEBSTER GF MARTIN P
Citation
Mj. Georgetson et al., EXACERBATION OF PSORIASIS DUE TO INTERFERON-ALPHA TREATMENT OF CHRONIC ACTIVE HEPATITIS, The American journal of gastroenterology, 88(10), 1993, pp. 1756-1758
Citations number
27
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
The American journal of gastroenterology → ACNP
ISSN journal
00029270
Volume
88
Issue
10
Year of publication
1993
Pages
1756 - 1758
Database
ISI
SICI code
0002-9270(1993)88:10<1756:EOPDTI>2.0.ZU;2-Y
Abstract
Interferon-a is an immune modulating drug which is indicated for the t reatment of chronic viral hepatitis B and C. Several previous reports have suggested an association between treatment of patients with inter feron-alpha and the development or exacerbation of autoimmune diseases . We report two patients with chronic viral hepatitis in whom treatmen t with interferon-alpha was associated with dramatic worsening of prev iously diagnosed psoriasis, necessitating discontinuation of the drug.