Jj. Ponzillo et Md. Malkoff, FOCUS ON FELBAMATE - BEGINNING A NEW-GENERATION OF ANTICONVULSANT AGENTS FOR THE TREATMENT OF EPILEPSY, Hospital formulary, 28(10), 1993, pp. 837
Felbamate is the first new drug approved by the FDA for the treatment
of epilepsy since valproic acid in 1978. Felbamate is indicated for th
e treatment of partial seizures in adults and Lennox-Gastaut syndrome
in children. Results of clinical trials indicate that felbamate decrea
ses seizure frequency in patients with partial seizures. The drug appe
ars to have a more favorable side effect profile than currently availa
ble drugs. Felbamate is a welcome addition to the pharmacologic armame
ntarium for the treatment of epilepsy.