BINSWANGER-DISEASE - THE KING-KHALID-UNIVERSITY-HOSPITAL EXPERIENCE

Two hundred and twenty-one Saudi patients admitted for stroke in King Khalid University Hospital between 1982 and 1987 were evaluated clinic ally and by laboratory and radiological investigations. Twelve patient s were found to have leukoaraiosis on brain CT and a clinical picture compatible with Binswanger disease (subcortical arteriosclerotic encep halopathy). Arterial hypertension was present in all cases, seizure di sorders in 25%, and dementia in 83%. The features of these cases are c ompared with similar cases reported from other places. The importance of control of hypertension in prevention of Binswanger disease is emph asized.