FUNGICIDAL ACTIVITY OF CECROPIN-A

Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated wi th CA. CA achieved complete lethality at less than or equal to 25 mu M (99 mu g/ml) for germinating, but not nongerminating, conidia of Aspe rgillus spp. CA achieved total lethality for nongerminated and germina ting conidia of Fusarium spp at 1.5 mu M (6 mu g/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar resul ts.