G. Vaccari et al., FERMENTATIVE PRODUCTION OF L-LACTIC ACID BY LACTOBACILLUS-CASEI DSM-20011 AND PRODUCT RECOVERY USING ION-EXCHANGE RESINS, Applied microbiology and biotechnology, 40(1), 1993, pp. 23-27
In order to produce L(+)-lactic acid to be employed in poly-L-lactic a
cid polymer production, for biomedical applications, the strain Lactob
acillus casei subsp. casei DSM 20011 was studied in a conventional bat
ch mode using different initial concentrations of glucose. The results
obtained showed that the initial glucose concentration exerts an infl
uence on the fermentation pattern, modifying the different fermentatio
n parameters. Nevertheless, the product yield remained at a constant v
alue of 0.86 g.g-1. The proposed novel system of product recovery, bas
ed on the use of ion-exchange resins, gave high yields of pure lactic
acid.