STUDIES ON LEWIS-ACID CATALYZED GENERATION AND INTERMOLECULAR TRAPPING OF CHIRAL STABILIZED AZOMETHINE YLIDS

Authors
HARWOOD LM MANAGE AC ROBIN S HOPES SFG WATKIN DJ WILLIAMS CE
Citation
Lm. Harwood et al., STUDIES ON LEWIS-ACID CATALYZED GENERATION AND INTERMOLECULAR TRAPPING OF CHIRAL STABILIZED AZOMETHINE YLIDS, Synlett, (10), 1993, pp. 777-780
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
10
Year of publication
1993
Pages
777 - 780
Database
ISI
SICI code
0936-5214(1993):10<777:SOLCGA>2.0.ZU;2-U
Abstract
Preparation of the ylid (2) derived from 5(R)-phenylmorpholinone (1) i n the presence of freshly prepared MgBr2.Et2O and dipolarophiles can l ead to improved cycloaddition yields, with inverse diastereo- and regi oselection compared to the corresponding uncatalysed reactions.