There is disagreement on the usefulness of comprehensive geriatric ass
essment (CGA) due to conflicting results from individual trials. We di
d a meta-analysis on 28 controlled trials comprising 4959 subjects all
ocated to one of five CGA types and 4912 controls. Published data were
supplemented with reanalysed data provided by the original investigat
ors. We calculated combined odds ratios of important outcomes by pooli
ng data from individual trials with multivariate logistic regression.
Combined odds ratio (95% confidence interval) of living at home at fol
low-up was 1.68 (1.17-2.41) for geriatric evaluation and management un
its, 1.49 (1.12-1.98) for hospital-home assessment services, and 1.22
(1.05-1.37) for home assessment services. Covariate analysis showed th
at programmes with control over medical recommendations and extended a
mbulatory follow-up were more likely to be effective. Our analysis sug
gests that CGA programmes linking geriatric evaluation with strong lon
g-term management are effective for improving survival and function in
older persons.