We studied the relation between diet and slight albuminuria in 5416 pe
ople, ages 40 years and over, who participated in a health screening s
urvey of a local workforce. Degree of albuminuria showed log-linear un
ivariate relations with dietary protein, cholesterol, and sodium intak
es, and negative log-linear univariate relations with dietary fiber an
d polyunsaturated to saturated fat (P/S) ratio. After adjusting for ag
e, gender, and ethnicity, the relative risk (95% confidence interval)
for slight albuminuria was significantly increased in people reporting
dietary cholesterol consumption >226 mg/day compared with people repo
rting consumption less-than-or-equal-to 226 mg/day [1.32 (1.02,1.70)],
and significantly reduced in people reporting dietary fiber consumpti
on >26 g/day compared with people reporting consumption less-than-or-e
qual-to 26 g/day [0.74 (0.58, 0.95)]. There was no significant effect
of dietary protein, P/S ratio, or salt intake. We conclude that risk o
f slight albuminuria is increased by consumption of dietary cholestero
l and reduced by consumption of dietary fiber.