We investigated the effect of age and gender on the tear break-up time
(TBUT) of 2 groups of normal, asymptomatic subjects [92 Hong Kong-Chi
nese (HK-Chinese) and 76 Singapore-Chinese (S-Chinese)] using the conv
entional fluorescein-instillation technique. The mean TBUT (+/-SD) is
6.5 (+/-4.0) s for the S-Chinese and 7.8 (+/-2.4) s for the HK-Chinese
. The mode was 7.0 s for HK-Chinese and 5.0 s for S-Chinese. About 80%
of the subjects of each group have TBUT less than 10 s. The TBUT of b
oth groups of Chinese decreases with age. It was found that TBUT was s
ignificantly different between the two sexes in the S-Chinese but no e
quivalent effect was observed in the HK-Chinese.