PRESENCE OF PAF-ACETHER IN HUMAN BLOOD AFTER THIN-LAYER CHROMATOGRAPHY, BUT NOT AFTER HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY PURIFICATION

Authors
IZZO AA BENVENISTE J
Citation
Aa. Izzo et J. Benveniste, PRESENCE OF PAF-ACETHER IN HUMAN BLOOD AFTER THIN-LAYER CHROMATOGRAPHY, BUT NOT AFTER HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY PURIFICATION, Journal of pharmacological and toxicological methods, 36(4), 1996, pp. 219-221
Citations number
13
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Journal of pharmacological and toxicological methods → ACNP
ISSN journal
10568719
Volume
36
Issue
4
Year of publication
1996
Pages
219 - 221
Database
ISI
SICI code
1056-8719(1996)36:4<219:POPIHB>2.0.ZU;2-H
Abstract
After HPLC purification of human blood extracts, paf-acether (paf) was found exclusively as a lipoprotein-bound compound (lipopaf), whereas free-paf was absent. When the same samples (or lipopaf recovered from HPLC) were purified by TLC, both free-paf and lipopaf were detected. T he free-paf detected in blood samples could thus result from lipopaf d issociation during TLC purification. (C) 1996 Elsevier Science Inc.