BOVINE CASEIN HAPLOTYPES - NUMBER, FREQUENCIES AND APPLICABILITY AS GENETIC-MARKERS

Authors
LIEN S ROGNE S
Citation
S. Lien et S. Rogne, BOVINE CASEIN HAPLOTYPES - NUMBER, FREQUENCIES AND APPLICABILITY AS GENETIC-MARKERS, Animal genetics, 24(5), 1993, pp. 373-376
Citations number
9
Categorie Soggetti
Genetics & Heredity","Veterinary Sciences
Journal title
Animal genetics → ACNP
ISSN journal
02689146
Volume
24
Issue
5
Year of publication
1993
Pages
373 - 376
Database
ISI
SICI code
0268-9146(1993)24:5<373:BCH-NF>2.0.ZU;2-P
Abstract
Three casein loci, tightly linked on bovine chromosome 6, have been st udied as haplotypes within families of bulls. The polymorphisms includ ed in the study were CASAS1 (B, C), CASB (A1, A, A5, B), CASK (A, B, E ) and a microsatellite in intron III of CASK. A new A5 variant of CASB , caused by a silent mutation in the triplet coding for amino acid 110 , was detected by direct polymerase chain reaction sequencing. Our ana lysis of 306 sons and 15 sires revealed 10 different casein haplotypes with a cumulative polymorphic information content (PIC) of 0.78.