FUNGICIDAL ACTIVITY OF POLYGODIAL IN COMBINATION WITH ANETHOLE AND INDOLE AGAINST CANDIDA-ALBICANS

Authors
HIMEJIMA M KUBO I
Citation
M. Himejima et I. Kubo, FUNGICIDAL ACTIVITY OF POLYGODIAL IN COMBINATION WITH ANETHOLE AND INDOLE AGAINST CANDIDA-ALBICANS, Journal of agricultural and food chemistry, 41(10), 1993, pp. 1776-1779
Citations number
13
Categorie Soggetti
Food Science & Tenology",Agriculture,"Chemistry Applied
Journal title
Journal of agricultural and food chemistry → ACNP
ISSN journal
00218561
Volume
41
Issue
10
Year of publication
1993
Pages
1776 - 1779
Database
ISI
SICI code
0021-8561(1993)41:10<1776:FAOPIC>2.0.ZU;2-B
Abstract
In our continuing search for antimicrobial agents from edible and medi cinal plants, beverages, and food spices, we have reported the limited antimicrobial activity of various compounds. Combining two or more of these chemicals to increase the activity spectrum seems to be a promi sing approach to practical use, although a rational basis for this is still in an early stage. The combination of polygodial (1) and anethol e (2) exhibited fungicidal activity against Candida albicans and Sacch aromyces cerevisiae. In contrast, the combination of polygodial and in dole (3) had fungistatic activity against C. albicans.