ADJUVANT CHEMOTHERAPY IN STAGE-I BREAST-CANCER - MORE HARM THAN BENEFIT

Authors
MUELLER CB
Citation
Cb. Mueller, ADJUVANT CHEMOTHERAPY IN STAGE-I BREAST-CANCER - MORE HARM THAN BENEFIT, Canadian family physician, 39, 1993, pp. 2185-2189
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Canadian family physician → ACNP
ISSN journal
0008350X
Volume
39
Year of publication
1993
Pages
2185 - 2189
Database
ISI
SICI code
0008-350X(1993)39:<2185:ACISB->2.0.ZU;2-W
Abstract
Clinical trials of adjuvant chemotherapy for breast cancer have shown a prolonged disease-free interval but no improvement in survival. This review of the evidence indicates that adjuvant therapy induces an ant ineoplastic drug resistance that makes ''salvage'' therapy less effect ive. The benefit that is seen only in group statistics, not in an indi vidual, must be weighed against the harm an individual incurs from the chemotherapy.