DIAGNOSTIC AND PROGNOSTIC VALUE OF CYTOGENETIC STUDY IN LYMPHOMATOID CONTACT-DERMATITIS VERSUS CUTANEOUS T-CELL LYMPHOMA

Authors
GRAMMATICO P BOTTONI U STEINDL K HEOUAINE A CARLESIMO M DIROSA C DEBERNARDO C DELPORTO G
Citation
P. Grammatico et al., DIAGNOSTIC AND PROGNOSTIC VALUE OF CYTOGENETIC STUDY IN LYMPHOMATOID CONTACT-DERMATITIS VERSUS CUTANEOUS T-CELL LYMPHOMA, Journal of experimental & clinical cancer research, 12(3), 1993, pp. 179-184
Citations number
NO
Categorie Soggetti
Oncology
Journal title
Journal of experimental & clinical cancer research → ACNP
ISSN journal
03929078
Volume
12
Issue
3
Year of publication
1993
Pages
179 - 184
Database
ISI
SICI code
0392-9078(1993)12:3<179:DAPVOC>2.0.ZU;2-C
Abstract
We report a case of lymphomatoid contact dermatitis with constitutiona l karyotype: 46, XY, inv(7) (p15q35). This chromosomal rearrangement i nvolves the regions where the genes codifying for the beta (7p15) and gamma (7q35) chains of the T-cell receptors are located. The importanc e of cytogenetics, and in particular of the breakpoint analysis, in or der to obtain some data useful for an early diagnosis of the T-cell tu mors, is stressed.