Ea. Varanda et Cs. Takahashi, EFFECT OF PRETREATMENT WITH VENOM OF APIS-MELLIFERA BEES ON THE YIELDOF GAMMA-RAY INDUCED CHROMOSOME-ABERRATIONS IN HUMAN BLOOD-LYMPHOCYTES, Brazilian journal of genetics, 16(3), 1993, pp. 551-559
Venom of the honey bee Apis mellifera induced a protective effect agai
nst the induction of dicentric chromosomes by gamma radiation (2.0 Gy)
in human peripheral blood lymphocytes which the cultures were treated
with 0.00015 mul venom/1 ml medium 6 h before irradiation. In culture
s to which the venom was added immediately before irradiation with 0.2
5, 1.0 and 2.0 Gy, no significant differences in number of dicentric c
hromosomes induced was observed when compared to cultures submitted to
irradiation only. The venom did not induce clastogenic effects nor di
d it increase the frequency of sister chromatid exchanges.