A 27-year-old man, who had been on steroid therapy for 2 months for hi
s nephrotic syndrome, suddenly developed intra-abdominal bile collecti
on (biloma). He had no previous history of abdominal surgery, trauma,
or any disease of the hepatobiliary system. The cause of the biloma fo
rmation was due, probably, to cholecystitis in the absence of calculi
and a pinhole size perforation in the wall of gall bladder. It was ass
umed to be closely related to the high-dose steroid therapy over a pro
longed period, which would likely suppress the repair process of the l
ocally damaged biliary system.