Lying between the carotid bifurcation and the jugular foramen, glomus
vagale tumors share characteristics with paragangliomas of those two s
tructures, such as invasion of the carotid artery, destruction of the
skull base, and cranial neuropathies. This capability for local invasi
on provides a therapeutic challenge with regard to the proper assessme
nt of tumor extent and the selection of appropriate treatment. In orde
r to clarify an approach to the management of glomus vagale tumors, we
reviewed a 10-year experience with 15 patients treated for this tumor
at the University of Zurich Department of Otolaryngology, using a new
system of classification. This system highlights the relative positio
n of a vagal paraganglioma to the jugular foramen and is helpful in de
signing the proper therapy. Pitfalls in surgical technique, recommende
d pre-operative evaluation, and the roles of balloon occlusion and irr
adiation in the treatment of these tumors are discussed.