Background and Objective: Laser-assisted tissue repair is often accomp
anied by a high dehiscence rate, which may be due to alterations in su
ture material after laser exposure. The goal of this study was to inve
stigate the effect of CO2 laser irradiation on the tensile strength of
microsurgical suture material. Study Design/Materials and Methods: 10
-0 nylon and 25 mu m stainless steel threads were exposed to 12 combin
ations of power densities (62, 124, and 186 W/cm(2)) and pulse duratio
ns (0.5, 1, 2, 3 s) and tested on a tensometer for their tensile stren
gth. Results: At power densities of 186 W/cm(2), the 10-0 nylon thread
disrupted during laser irradiation, regardless of pulse duration. Thi
s was also the case at power densities of 124 W/cm(2) for 2 s and 3 s
pulse duration. At 124 W/cm(2) for 0.5 and 1 s, the tensile strength d
ecreased with 70% relative to the control, At 62 W/cm(2), the tensile
strength gradually decreased from 100% (0.5 s pulse duration) to 50% (
3 s pulse duration) relative to control. Stainless steel thread resist
ed all laser irradiations. Conclusions: The 10-0 nylon thread is signi
ficantly compromised by irradiation with the CO2 milliwatt laser and t
herefore meticulous care should be taken not to irradiate the sutures
during laser tissue welding. (C) 1997 Wiley-Liss, Inc.