MEASUREMENT OF WHOLE TEMPORAL-LOBE AND HIPPOCAMPUS FOR MR VOLUMETRY -NORMATIVE DATA

We measured the volumes of the entire length of temporal lobe and hipp ocampal formation from coronal images in 29 healthy young adults to ta ke into account normal side-to-side variation. Although whole-brain, t emporal lobe, and left hippocampal volumes were significantly smaller in women, normalizing measurements for the whole brain eliminated inte rsex temporal lobe and hippocampal differences. There was a weak but s ignificant inverse correlation between age and normalized hippocampal, but not temporal lobe or whole-brain, volume. In contrast to previous studies, we found no significant side-to-side differences in the size s of temporal lobes or hippocampi. When performing MR volumetry, it is important to include the entire length of the hippocampal formation.