V. Cangemi et al., THE CURRENT STATUS OF THE WHIPPLE PROCEDURE FOR AMPULLARY AND PERIAMPULLARY CARCINOMA, Journal of experimental & clinical cancer research, 15(4), 1996, pp. 399-404
Between 1980 and 1994, 22 patients underwent Whipple operation for duc
tal adenocarcinoma of the head of the pancreas and adenocarcinoma of t
he papilla of Vater at the Ist Department of Surgery, University of Ro
me ''La Sapienza''. All resections were performed by the same surgical
equipe, Preoperative biliary drainage was performed in 14 patients wi
th severe jaundice. There was no mortality related to the adopted proc
edure. Two patients presented moderate postoperative complications: le
akage of the pancreatojejunostomy and lymphorrea which were resolved i
n about 2 weeks. One patient died in the postoperative course because
of severe hepatorenal failure due to previous biliary cirrhosis and ch
olangitis. Our data agree with recent literature reports and show that
Whipple operation or its variants still constitute a valid choice in
the treatment of tumors of the head of the pancreas and of the papilla
of Vater.