A. Converti et al., THE EFFECTS OF MIXING ON BIOPROCESSES - CONCENTRATION DISTRIBUTIONS AND MECHANICAL SHEAR-STRESS, Bioprocess engineering, 9(5), 1993, pp. 183-189
The effects of mixing on batch alcohol fermentation of diluted solutio
ns of starch hydrolysate is studied. The results of a limited number o
f samples simultaneously drawn at different locations in the reactor a
nd after different reaction times have been used in a simple mathemati
cal model to provide a, picture of the concentration distributions wit
hin the reaction environment. The optimal mixing conditions for the fe
rmentation are met at rotation speeds between 1.7 and 5.0 s-1, while t
he broth homogeneity obviously increases indefinitely with increasing
this parameter. This suggests. the existence of a shear stress for the
biomass, whose effect increases. with the application time and seems
to affect the process mainly at the end of the fermentation.