MALIGNANT MIXED EXOCRINE-ENDOCRINE TUMOR OF THE PANCREAS WITH UNUSUALINTRACYTOPLASMIC INCLUSIONS

Authors
HASSAN MO GOGATE PA
Citation
Mo. Hassan et Pa. Gogate, MALIGNANT MIXED EXOCRINE-ENDOCRINE TUMOR OF THE PANCREAS WITH UNUSUALINTRACYTOPLASMIC INCLUSIONS, Ultrastructural pathology, 17(5), 1993, pp. 483-493
Citations number
20
Categorie Soggetti
Microscopy,Pathology
Journal title
Ultrastructural pathology → ACNP
ISSN journal
01913123
Volume
17
Issue
5
Year of publication
1993
Pages
483 - 493
Database
ISI
SICI code
0191-3123(1993)17:5<483:MMETOT>2.0.ZU;2-9
Abstract
A case of malignant mixed exocrine-endocrine tumor of the pancreas is reported. Electron microscopy revealed abundant neurosecretory granule s in most cells. Zymogen granules indicating acinar differentiation we re seen in a few cells. Ductal features, including microvilli with pro minent filamentous cores and intracytoplasmic mucin granules, were als o noted in this lesion. Immunocytochemical stains were positive for se rotonin and glucagon. Unusual intracytoplasmic fibrillary inclusions a re described and their possible origin discussed.