HYPERTEXT TOOLS FOR THE SELECTION OF DISSOLUTION METHODS PRIOR TO THEATOMIC-ABSORPTION ANALYSIS OF PHARMACA

A hypertext system for the selection of dissolution methods prior to t he atomic absorption analysis of pharmaca was developed. The knowledge about dissolution methods, available in an industrial quality assuran ce laboratory, was first structured in a decision tree. The tree was i mplemented in a knowledge-based computer system using Toolbook softwar e, an object oriented language for the personal computer. Beside its u ser-friendliness and possibility to build an attractive user-interface , this language permits the extension of the system with some importan t options, which would be difficult or impossible to create with other tools. The most important options are: (a) a partial maintainability of the system that is given to the user, (b) the visualization of the strategy of the decision making by displaying the structure of the tre e in combination with a list of consulted pages, and (c) a database wh ich ensures the completeness of the presented information and can easi ly be separately consulted.