EFFECTS OF TRIBUTYLTIN(IV) CHLORIDE EXPOSURE ON EARLY EMBRYONIC STAGES OF CIONA-INTESTINALIS - IN-VIVO AND ULTRASTRUCTURAL INVESTIGATIONS

Authors
MANSUETO C GIANGUZZA M DOLCEMASCOLO G PELLERITO L
Citation
C. Mansueto et al., EFFECTS OF TRIBUTYLTIN(IV) CHLORIDE EXPOSURE ON EARLY EMBRYONIC STAGES OF CIONA-INTESTINALIS - IN-VIVO AND ULTRASTRUCTURAL INVESTIGATIONS, Applied organometallic chemistry, 7(6), 1993, pp. 391-399
Citations number
19
Categorie Soggetti
Chemistry Applied","Chemistry Inorganic & Nuclear
Journal title
Applied organometallic chemistry → ACNP
ISSN journal
02682605
Volume
7
Issue
6
Year of publication
1993
Pages
391 - 399
Database
ISI
SICI code
0268-2605(1993)7:6<391:EOTCEO>2.0.ZU;2-E
Abstract
The effects of tributyltin(IV) chloride (TBT chloride) solutions on as cidian embryos of Ciona intestinalis have been tested at different sta ges of development. It has been observed, in vivo, that TBT chloride i nhibited cleavage of fertilized eggs and of embryo blastomeres giving rise to cellular masses that are not delimited by plasma membrane. Ele ctron-dense precipitates of TBT chloride, probably as inorganic tin, h ave been observed by transmission electron microscopy in the egg cytop lasm of cellular masses. The same type of precipitate was present also inside the mitochondria, whose structure appeared to be highly modifi ed. These ultrastructural aspects are indicative of a degenerative pro cess of the embryos after incubation in TBT chloride.