H. Nomori et H. Horio, GELATIN-RESORCINOL-FORMALDEHYDE-GLUTARALDEHYDE GLUE-SPREAD STAPLER PREVENTS AIR LEAKAGE FROM THE LUNG, The Annals of thoracic surgery, 63(2), 1997, pp. 352-355
Background. To reinforce the staple line of the emphysematous lung and
thereby prevent air leakage during thoracoscopic operations, we have
developed a procedure of lung excision that uses a gelatin-resorcinol-
formaldehyde-glutaraldehyde (GRFG) glue-spread stapler. Methods. Forma
ldehyde-glutaraldehyde (FG) jelly is prepared by mixing FG fluid with
2.5% sodium carboxymethyl cellulose. The FG jelly is placed in the sta
pler groove and staple holes, and a gelatin-resorcinol (GR) mixture is
applied. The GRFG glue-spread stapler was applied to emphysematous lu
ng cutting during thoracoscopic operations in 10 cases. Results. An ad
hesion-strength test showed no difference in glue adhesion between FG
fluid and FG jelly. An experiment using swine lung showed that with th
is newly developed stapler, no resistance in firing occurred, and GRFG
glue covered every staple hole. Clinical application in 10 eases with
emphysematous lung demonstrated no air leakage from the staple line,
even long after the operation. Conclusions. Emphysematous lung excisio
n using the GRFG glue-spread stapler during thoracoscopic operations i
s useful in preventing air leakage from the staple line and is a simpl
e, safe, and low-cost procedure. (C) 1997 by The Society of Thoracic S
urgeons.