C. Caubere et al., COMPLEX BASES PROMOTED ARYNIC CYCLIZATIONS OF HALOGENATED IMINES OR ENAMINES - A REGIOCHEMICAL SYNTHESIS OF INDOLE-DERIVATIVES, Tetrahedron letters, 34(43), 1993, pp. 6889-6892
The complex base NaNH2-tBuONa allows expeditious synthesis of indole d
erivatives by arynic cyclization of imines or enamines of chloroanilin
es. Unstable imines may be used without purification. complex bases be
ing unsensitive to impurities.