To determine the incidence of complications associated with contempora
ry prostate biopsy, a review of 670 men undergoing transrectal prostat
e biopsy using 18 gauge biopsy needles was conducted. Of the men 580 r
eceived 1 to 3 days of ciprofloxacin antibiotic prophylaxis. A total o
f 16 patients (2.1%) suffered complications of whom 4 (0.6%) required
hospitalization. These data demonstrate the low morbidity associated w
ith contemporary transrectal prostate biopsy.