A prospective study of excimer laser photorefractive keratectomy was p
erformed with the aim of correcting a range of myopic errors between -
1.00 and -10.00 dioptres. Corneal healing was monitored through the fi
rst post-operative year by serial assessments of refraction, contrast
sensitivity, corneal haze, pachymetry and keratometry. Eighty-one pati
ents were recruited for the study. At 12 months 81% were within +/- 1.
00 dioptre of desired emmetropia and with unaided vision of 6/12. Cont
rast sensitivity was found by Pelli-Robson assessment to be reduced th
roughout the 12 months and regression analysis predicted recovery by 2
years. At 12 months, however, only 15% of patients were found to have
lost a single line of best corrected Snellen acuity. Predictability o
f results was found to be greatest for initial errors less than -4.00
dioptres. No serious complications were observed during the follow-up
period, but refraction had not stabilised in all cases and patients re
main under review.