CONJUNCTIVAL INVOLVEMENT IN MALIGNANCY-ASSOCIATED ACANTHOSIS NIGRICANS

Acanthosis nigricans classically presents with pigmented skin lesions over the neck, groin and axillae. It may involve the mucosal surfaces, particularly the oral mucosa. Conjunctival involvement is very rare, especially in the variety associated with malignancy. We report a case of acanthosis nigricans associated with squamous cell carcinoma of th e bronchus where bilateral papillary conjunctivitis, progressing to hy pertrophic papillary conjunctival and lid margin lesions, was the pres enting feature. Topical treatment with corticosteroid and artificial t ear drops resulted in the partial improvement of the ocular symptoms.