Standards for human fetal intestinal length are not we established but
have important implications for the care of the preterm and intra-ute
rine growth-retarded (IUGR) infant. Our purpose was to examine the rel
ationship between intra-uterine growth and intestinal length in the hu
man fetus. One hundred infants were studied. Birth weight and gestatio
nal age ranged from 76 to 4,385 g and from 12 to 42 weeks, respectivel
y. Twenty-one infants were noted to be IUGR. Intestinal length (total,
small, large) increased (p < 0.0001) with birth weight, gestational a
ge, and crown-heel length but was reduced in IUGR infants. The ratio o
f body weight to intestinal length increased with gestation but was al
so reduced in IUGR infants. In conclusion, a reduced functional mass,
as suggested by decreased intestinal length or body weight:intestinal
length ratio, may contribute to the poor weight sometimes seen in the
very-low-birth weight or IUGR infant.