Neurolysis is a procedure which has to be performed if the gliding app
aratus of a peripheral nerve does not function, and consequently, adhe
sions and fibrosis develop. The gliding tissue has to provide the abil
ity for the nerve to adapt to the different position of the extremity
by longitudinal passive movement. The paraneurium provides movements b
etween the nerve and the surrounding tissue; the interfascicular epine
urium provides the possibility of the movement within the nerve. Inter
nal neurolysis is defined as surgery within the nerve if the epifascic
ular epineurium is completely transected. A classification of differen
t degrees of fibrosis is given with special reference to the procedure
which has to be done in each case. Neurolysis is a step-wise procedur
e with the aim to decompress the fascicles and which is immediately st
opped if this aim is achieved. In very severe cases, if the gliding ti
ssue does not regenerate, a gliding tissue flap to envelope the nerve
may solve the problem. (C) 1993 Wiley-Liss, Inc.