Carisoprodol, a centrally acting muscle relaxant, has recently been no
ticed to be abused. A series of 16 cases with carisoprodol abuse or de
pendence is described. Carisoprodol was started by the majority of pat
ients as a substitute for opiates, although its independent distinct e
ffects, similar to the features of hypomania, were recognized and desc
ribed by most users. The drug is currently available freely over the c
ounter and is a much cheaper substitute for the legally prohibited ''h
arder'' drugs. Unless awareness spreads and cautionary measures are ta
ken, carisoprodol abuse might become a great menace in the near future
.