Mi. Yasawy et al., COMBINATION OF PRAZIQUANTEL AND ALBENDAZOLE IN THE TREATMENT OF HYDATID-DISEASE, Tropical medicine and parasitology, 44(3), 1993, pp. 192-194
This is a preliminary report on the first four patients with pelvic, a
bdominal and thoracic hydatid disease, who are receiving combined medi
cal treatment (albendazole 400 mg bd on monthly courses plus praziquan
tel 50 mg/kg in different regimens). Response to treatment was monitor
ed clinically, biochemically and radiologically by means of computed t
omography (CT) and abdominal sonography (US). No side effects were obs
erved in the course of this treatment. After 3 months of using the com
bined treatment, cysts disappeared completely in three patients and in
the fourth patient, a reduction in cysts size by more than 75 % after
two months combination treatment was observed. This combination thera
py as a human trial has not been reported previously. This preliminary
report shows that the response to combined treatment is better and mu
ch quicker compared to albendazole alone.