A stratified random sample of Ohio dairy herds was studied to relate h
erd management and environmental conditions to intramammary infection
with coagulase-positive staphylococci. Management and environmental co
nditions were assessed by investigator observation and by interview wi
th the dairy producers. Separate analyses for each of 70 management an
d environmental independent variables identified many potential diseas
e determinants. A logistic regression model used five model degrees of
freedom to predict the prevalence of coagulase-positive staphylococci
in more than 1% of quarters. Increased risk of infection with coagula
se-positive staphylococci was associated with dirty udders, high-line
milking systems, and less crowded housing conditions. Decreased risk o
f infection was associated with a herd size of 50-100 cows.