BAKERS-YEAST REDUCTION OF 2-ETHOXYCARBONYL-CYCLANONES PRECURSORS OF FREE-RADICAL CHIRONS OF THE 2(S)-HYDROXYCYCLOALKYL MOIETY

Authors
HAMDANI M DEJESO B DELEUZE H MAILLARD B
Citation
M. Hamdani et al., BAKERS-YEAST REDUCTION OF 2-ETHOXYCARBONYL-CYCLANONES PRECURSORS OF FREE-RADICAL CHIRONS OF THE 2(S)-HYDROXYCYCLOALKYL MOIETY, Research of chemical intermediates, 19(7), 1993, pp. 681-692
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Research of chemical intermediates → ACNP
ISSN journal
09226168
Volume
19
Issue
7
Year of publication
1993
Pages
681 - 692
Database
ISI
SICI code
0922-6168(1993)19:7<681:BRO2PO>2.0.ZU;2-3
Abstract
The reduction of 2-ethoxycarbonyl-cyclopentanone and -cyclohexanone by baker's yeast yielded in good yields (1S, 2R) 2-ethoxycarbonyl-cyclop entanol and cyclohexanol. The above two hydroxyesters were used as sta rting materials to prepare, via free radical reactions, various 2-subs tituted (Cl, Br, CH2CH2CO2Et, S-Py) 1-ethoxymethoxy-cyclopentanes (d.e . 92-98%) and-cyclohexanes (d.e. 11-60%).