Thalamotomy and electrical stimulation of a thalamic target as treatme
nt for persistent pain are discussed. Thalamotomy is only rarely perfo
rmed these days according to a questionnaire, given to some colleagues
, about the type and the number of operations they performed in the ye
ars 1984, 1985 and 1986. The need for stimulation in the periventricul
ar or periaqueductal grey for nociceptive pain is decreasing due to th
e advent of intraspinal and intraventricular administration of opioids
. Nowadays medial and lateral ventro-posterior thalamic nuclei are fre
quently stimulated for treatment of deafferentation pain. Of 36 patien
ts with deafferentation pain, 22 initially had benefit from this stimu
lation, but long-term success was only achieved in 11 (30%) of them. I
t was a general trend that the patients with an initial high pain reli
ef score obtained the best long-term results.