During 1988 through 1990, California experienced its worst measles epi
demic in more than a decade, with 16,400 reported cases, 3,390 hospita
l admissions, and 75 deaths. More than half of the patients were young
er than 5 years; the highest incidence was among infants younger than
12 months. The epidemic centered in low-income Hispanic communities in
southern and central California. The major cause of the epidemic was
low immunization levels among preschool-aged children and young adults
. Rates of complications, admission to hospital, and death were surpri
singly high. Outbreak control efforts met with indeterminate success.
Problems with these efforts included insufficient funding early in the
epidemic and disappointing public response to community-based immuniz
ation campaigns. The cost of medical care and outbreak control for the
epidemic is conservatively estimated at $30.9 million. Unless the lev
el of immunization in preschool-aged children is increased, this type
of epidemic will probably recur.