SYNTHESIS AND ANTITUMOR ACTIVITIES OF 4-A LKYLSELENYL-4-DEOXY-4'-DEMETHYLEPIPODOPHYLIOTOXIN

Authors
WANG ZG MA WY ZHANG CN
Citation
Zg. Wang et al., SYNTHESIS AND ANTITUMOR ACTIVITIES OF 4-A LKYLSELENYL-4-DEOXY-4'-DEMETHYLEPIPODOPHYLIOTOXIN, Huaxue xuebao, 51(9), 1993, pp. 933-936
Citations number
3
Categorie Soggetti
Chemistry
Journal title
Huaxue xuebao → ACNP
ISSN journal
05677351
Volume
51
Issue
9
Year of publication
1993
Pages
933 - 936
Database
ISI
SICI code
0567-7351(1993)51:9<933:SAAAO4>2.0.ZU;2-G
Abstract
4-Bromo-4-deoxy-4'-demethylepipodophyliotoxin reacted with selenourea, followed by displacement with active halides in the presence of Et3N to kylselenyl-4-deoxy-4'-demethylepipodophyllotoxins. Six compounds co ntaining Se showed marked antitumor activities.