CHARACTERIZATION OF ION-PAIR FORMATION BETWEEN IONIZED INDOMETHACIN AND CATIONIC SURFACTANTS

Authors
TAN EL LIU JC CHIEN YW
Citation
El. Tan et al., CHARACTERIZATION OF ION-PAIR FORMATION BETWEEN IONIZED INDOMETHACIN AND CATIONIC SURFACTANTS, Journal of dispersion science and technology, 14(6), 1993, pp. 609-624
Citations number
14
Categorie Soggetti
Chemistry Physical
Journal title
Journal of dispersion science and technology → ACNP
ISSN journal
01932691
Volume
14
Issue
6
Year of publication
1993
Pages
609 - 624
Database
ISI
SICI code
0193-2691(1993)14:6<609:COIFBI>2.0.ZU;2-E
Abstract
The interactions between sodium indomethacin and chloride salts of fou r quaternary ammonium compounds were characterized. Investigations inv olved conductimetric studies at concentration regions wherein ion-pair s exist in equilibrium with the solution of participating ions. Iontop horesis was also utilized to investigate the phenomenon of ion-pairing . Characteristic of large molecules, extremely high levels of ion-pair association constants and low degrees of dissociation were obtained.