ANTIOXIDANT ACTIVITIES OF POLYGONUM-MULTIFLORUM THUNB, IN-VIVO AND IN-VITRO

Citation
Sp. Ip et al., ANTIOXIDANT ACTIVITIES OF POLYGONUM-MULTIFLORUM THUNB, IN-VIVO AND IN-VITRO, PTR. Phytotherapy research, 11(1), 1997, pp. 42-44
Citations number
12
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
11
Issue
1
Year of publication
1997
Pages
42 - 44
Database
ISI
SICI code
0951-418X(1997)11:1<42:AAOPTI>2.0.ZU;2-5
Abstract
We have demonstrated the presence of both in vivo and in vitro antioxi dant activities in the crude water-extract of the root of Polygonum mu ltiflorum Thunb. (PMC), as indicated by its ability to protect against CCl4-induced hepatotoxicity in rats and to scavenge ferri-heme oxidan ts generated in an in vitro system. Activity directed fractionation of the PMC indicated that the antioxidant components were contained in t he ethylacetate fraction. (C) 1997 by John Wiley & Sons, Ltd.