ANTIAGGREGANT EFFECTS ON HUMAN PLATELETS OF THE CRUDE AQUEOUS EXTRACTAND POLAR FRACTIONS OF THE MICROALGA DUNALIELLA-TERTIOLECTA

Authors
VILLAR R LAGUNA R MARTINEZ D NUNEZ L JIMENEZ C
Citation
R. Villar et al., ANTIAGGREGANT EFFECTS ON HUMAN PLATELETS OF THE CRUDE AQUEOUS EXTRACTAND POLAR FRACTIONS OF THE MICROALGA DUNALIELLA-TERTIOLECTA, PTR. Phytotherapy research, 11(1), 1997, pp. 70-72
Citations number
8
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
11
Issue
1
Year of publication
1997
Pages
70 - 72
Database
ISI
SICI code
0951-418X(1997)11:1<70:AEOHPO>2.0.ZU;2-X
Abstract
The crude aqueous extract of the microalga Dunaliella tertiolecta was found to have strong inhibitory effects on the aggregation of human pl atelets induced by thrombin, arachidonic acid and ionomycin. The extra ction of the crude aqueous extract with (PrOH)-Pr-i and posterior frac tionation with solvents of increasing polarity, concentrated the activ ity in the more polar fractions. (C) 1997 by John Wiley & Sons, Ltd.