GUT INTRAEPITHELIAL LYMPHOCYTES AND GASTROINTESTINAL-DISEASES

Authors
CERFBENSUSSAN N CERF M GUYGRAND D
Citation
N. Cerfbensussan et al., GUT INTRAEPITHELIAL LYMPHOCYTES AND GASTROINTESTINAL-DISEASES, Current opinion in gastroenterology, 9(6), 1993, pp. 953-961
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Current opinion in gastroenterology → ACNP
ISSN journal
02671379
Volume
9
Issue
6
Year of publication
1993
Pages
953 - 961
Database
ISI
SICI code
0267-1379(1993)9:6<953:GILAG>2.0.ZU;2-4
Abstract
intraepithelial lymphocytes interspersed between intestinal epithelial cells form a large population of T cells, mainly CD8+, close to the i ntestinal lumen. Together with lamina propria T cells and plasma cells , they represent the effector limb of the gut-associated lymphoid syst em. Recent data highlighting their original properties and their inter actions with epithelial cells are reviewed; their contributions to imm une defenses and gastrointestinal diseases in humans are discussed.