ANTITUMORAL EFFECT OF BLEOMYCIN PLUS DOLOMITE COMBINATION TREATMENT, IN MICE BEARING EHRLICH ASCITES-CARCINOMA

Authors
SCHELLER S KROL W SKIRMUNTT K ZYDOWICZ G SHANI J
Citation
S. Scheller et al., ANTITUMORAL EFFECT OF BLEOMYCIN PLUS DOLOMITE COMBINATION TREATMENT, IN MICE BEARING EHRLICH ASCITES-CARCINOMA, Zeitschrift fur Naturforschung. C, A journal of biosciences, 48(9-10), 1993, pp. 818-820
Citations number
15
Categorie Soggetti
Biology
Journal title
Zeitschrift fur Naturforschung. C, A journal of biosciences → ACNP
ISSN journal
09395075
Volume
48
Issue
9-10
Year of publication
1993
Pages
818 - 820
Database
ISI
SICI code
0939-5075(1993)48:9-10<818:AEOBPD>2.0.ZU;2-G
Abstract
Dolomite, a mineral composed of magnesium and calcium carbonates, pote ntiates the antitumoral activity of bleomycin: While 40 days after ino culation, no mice survived the Ehrlich ascites tumor burden, 44% of th em survived it after bleomycin treatment, and 63% after a simultaneous treatment of bleomycin and dolomite. The beneficial antitumor effect of dolomite is probably related to its high content (12.8%) of magnesi um.