HYDANTOIN ANALOGS OF THYMIDINE

Authors
ELBARBARY AA KHODAIR AI PEDERSEN EB
Citation
Aa. Elbarbary et al., HYDANTOIN ANALOGS OF THYMIDINE, Journal of organic chemistry, 58(22), 1993, pp. 5994-5999
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
22
Year of publication
1993
Pages
5994 - 5999
Database
ISI
SICI code
0022-3263(1993)58:22<5994:HAOT>2.0.ZU;2-T
Abstract
Hydantoin nucleosides were synthesized from a protected methyl 2-deoXy -D-ribofuranoside in a Friedel-Crafts catalyzed silyl-Hilbert-Johnson reaction as modified by Vorbruggen. Atypical byproducts are accounted for by assuming the initial step being a ring opening of the sugar to give an acyclic glycos-1-yl cation.